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February 2017

Patient Care

Ovarian and testicular cryopreservation preserves fertility in prepubertal children
Recent advances in reproductive endocrinology allow cryopreservation of prepubertal boys' testicular tissue and girls' ovarian tissue before children begin cancer therapy known to impact fertility adversely.

Lymph2Cx genetic test determines the source of diffuse large B-cell lymphoma
The Lymph2Cx test assigns cell-of-origin groups using a 20-gene expression-based assay to help guide diagnosis and treatment of patients with diffuse large B-cell lymphoma.

Improved glioma classification system tests for genetic mutations
Results of a study of the classification of genetic alterations common to gliomas indicate that molecular methods can do a better job than current methods of predicting which specific treatment course is necessary for each individual patient.

Spinal ablation offers less invasive cancer treatment
The use of radiofrequency ablation and cryoablation to successfully treat patients with cancer that has metastasized to the spine also provides a new treatment opportunity for patients with more complex disease involving larger tumors or multiple spinal bones.


SRS provides better quality of life for some patients with brain tumors
Research indicates that patients with three or fewer metastatic brain tumors who received treatment with stereotactic radiosurgery (SRS) had less cognitive deterioration three months after treatment than did patients who received SRS combined with whole-brain radiation therapy.

Tumor treatment tailored to the needs of the developing pediatric nervous system
Brain and central nervous system tumors now represent the most common cause of cancer-related death in children. New information about the molecular diversity of these tumors points the way toward targeted therapies tailored to tumor subtypes.

Comparison shows nonaspirin NSAIDs most effective in colorectal tumor prevention
Nonsteroidal anti-inflammatory drugs (NSAIDs) are more effective than aspirin or nutritional supplements in preventing the growth of advanced adenomas, although aspirin is nearly as effective with less risk. Most colorectal tumors develop from untreated adenomatous polyps.

Risk estimates help identify gene variants that increase breast cancer risk
Researchers studied data from 65,000 women to obtain risk estimates associated with 21 cancer predisposition genes from testing panels. Results indicate that inherited pathogenic variants in certain protein coding genes increase the likelihood of developing breast cancer.

Ceritinib shows promise as a treatment for inflammatory myofibroblastic tumors
After using ceritinib to shrink a patient's inflammatory myofibroblastic tumors successfully, researchers conducted mate pair sequencing, a test that scans the entire genome to pinpoint genetic defects and chromosomal breaks, to identify the cause of the rare sarcoma.

See all Cancer Clinical Trials at Mayo Clinic

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Hematologic Malignancies: New Therapies and the Evolving Role of Transplant 2017
March 17-18, 2017, in Chicago
This course focuses on the role of new therapies in treating patients with hematologic malignancies and the evolving role of blood and marrow transplantation.

Capture the Moment Cancer Education Symposium
March 25, 2017, in Orlando, Fla.
This symposium, which provides comprehensive patient-focused information on the diagnosis and treatment of cancer, is an excellent resource for patients, family members and caregivers. Please invite patients who are in active treatment, recovering or have been cured.

Mayo Clinic Oncology Review 2017

July 22, 2017, in Minneapolis
This program provides an overview of advances in the treatment of various oncologic malignancies, based on abstracts presented at the June 2017 annual meeting of the American Society of Clinical Oncology.

See all Hematology and Oncology Continuous Professional Development courses

In the Video Center

Molecular switch stems the growth of breast cancer cells
Researchers identified a small site in the HER2 protein that enables it to pair up, forming a molecular switch that sets off a cascade of events that turn normal cells cancerous. Disrupting this site can stem the growth of breast cancer cells more effectively than drugs currently in use.

View videos by specialty and Grand Rounds presentations online

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