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May 2017

Patient Care

Survival rates for pediatric bone cancer improve dramatically
Advances including adjuvant chemotherapy regimens, improved imaging and custom implants have improved the five-year survival rate for local pediatric bone cancers to 60 to 80 percent.

Stem cells may prevent chemotherapy-induced neuropathy in patients with cancer
Mesenchymal stem cells act as therapy for nervous system diseases by carrying extracellular products across the blood-brain barrier in patients with amyotrophic lateral sclerosis. The stem cells may also be used to deliver nerve protection to patients before chemotherapy.


Interaction among proteins causes cancer cells to metastasize
Researchers have identified a direct interaction between focal adhesion kinase and myosin that drives the production of secreted cancer-promoting proteins, which cancer cells use to create stiff, insoluble scaffolds that inhibit anti-tumor immunity and support tumor growth and metastasis.

BEAUTY studies tumor sequencing prior to chemotherapy in women with breast cancer
Investigators report that most common genetic changes were not more commonly observed in chemotherapy-resistant, compared to chemotherapy-sensitive, tumors. They also confirmed the feasibility of patient-derived xenografts using needle biopsies from the primary breast tumor prior to surgery.

Patients with multiple myeloma living longer
Thanks to early diagnosis, excellent treatment options now available and centers that specialize in the treatment of multiple myeloma, most patients can achieve remission. Life expectancy rates have also improved.

Researchers identify FOXO1's role in chemotherapy resistance
When FOXO1 remains in a cell's nucleus, another protein, ERK, becomes inappropriately active and sends signals that help cancer survive. When FOXO1 migrates out of the nucleus, however, it attaches to the scaffolding protein IQGAP1, which blocks the activation of ERK.

See all Cancer Clinical Trials at Mayo Clinic

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Mayo Clinic Oncology Review 2017
July 22, 2017, in Minneapolis
This program provides an overview of advances in the treatment of various oncologic malignancies, based on abstracts presented at the June 2017 annual meeting of the American Society of Clinical Oncology.

Hematology, Oncology, & Blood & Marrow Transplant for NPs & PAs 2017
Aug. 18-20, 2017, in Rochester, Minn.
This conference provides both novice and seasoned nurse practitioners (NPs) and physician assistants (PAs) with cutting-edge information on caring for patients in Oncology, Hematology and Blood and Marrow Transplant.

Mayo Clinic Neuroscience and Oncology Innovation Summit 2017
Sept. 7-9, 2017, in Orlando, Fla.
Topics include brain tumor biology and growth, vascular neogenesis, nanotechnology for tumor suppression, viral vectors for tumor destruction and other agents to target and destroy brain tumors. The course also covers basic tumors of other sites and metastatic brain tumor therapies.

See all Hematology and Oncology Continuous Professional Development courses

In the Video Center

Cancer Care at Mayo Clinic in Arizona
The Cancer Center at Mayo Clinic's campus in Phoenix, Arizona, integrates all cancer services from prevention to survivorship to create a seamless care experience for patients. Mayo experts discuss the new facility.

View videos by specialty and Grand Rounds presentations online

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